Sphynx cat vaccination schedules are an essential part of keeping your Sphynx cat healthy and protected from common feline diseases. Given their lack of fur and potentially higher sensitivity to environmental factors, ensuring your Sphynx follows a proper vaccination schedule is crucial. In this post, we’ll break down the vaccines your Sphynx needs, when they should receive them, and how to keep them healthy through all stages of life.

For more information on general care for your Sphynx cat, check out our Ultimate Guide for Hairless Cat Owners, where we cover everything from grooming to feeding.

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Why Vaccines are Important for Sphynx Cats

Like all cats, Sphynx cats are at risk for contracting several preventable diseases. Vaccines help boost their immune system and offer long-term protection against potentially life-threatening conditions. Since Sphynx cats don’t have fur to protect them from environmental factors, they might be more susceptible to skin infections, and an overall strong immune system is vital.

To learn more about how vaccinations support overall health, visit our Sphynx Cat Health Guide.

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Core Vaccines for Sphynx Cats

There are a few core vaccines that all cats, including Sphynx cats, should receive. These vaccines protect against highly contagious and often serious diseases.

1. FVRCP (Feline Viral Rhinotracheitis, Calicivirus, and Panleukopenia)

The FVRCP vaccine is considered essential for all cats. It offers protection against three major viruses:

• Feline Viral Rhinotracheitis: Causes severe respiratory issues.
• Calicivirus: Leads to respiratory infections and oral disease.
• Panleukopenia: Also known as feline distemper, this virus can be deadly, especially to kittens.

When to Administer:

• First dose: At 9 weeks of age
• Second dose: At 12 weeks of age
• Booster: At 15 weeks of age
• Annual boosters thereafter to maintain immunity

Pro Tip: Keep an updated vaccination record with your vet to ensure your Sphynx remains up to date. If you’re adopting a kitten, make sure the breeder provides you with all vaccine documentation. For more on what to expect when adopting, check out our Sphynx Cat Adoption Guide.

2. Rabies

Rabies is a fatal viral disease that can affect both cats and humans. Even indoor cats, like Sphynx cats, are at risk and should be vaccinated. Many states require the rabies vaccine by law, so it’s important to ensure your Sphynx is protected.

When to Administer:

• First dose: At 12 weeks of age
• Booster: Annually or every three years, depending on the vaccine type used by your vet

Related Reading: For more about ensuring the long-term health of your Sphynx, read our Sphynx Cat Health and Vaccination Protocols.

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Non-Core Vaccines for Sphynx Cats

In addition to the core vaccines, there are non-core vaccines that may be recommended based on your Sphynx’s lifestyle and environment.

1. Feline Leukemia Virus (FeLV)

The FeLV vaccine is recommended for cats that spend time outdoors or are exposed to other cats, such as in multi-cat households. FeLV weakens the immune system and can be fatal over time.

When to Administer:

• First dose: At 12 weeks of age (after testing for FeLV status)
• Booster: At 15 weeks of age
• Annual boosters thereafter if your Sphynx is at risk

Even if your Sphynx is an indoor-only cat, consider FeLV testing, especially if they come into contact with other cats. Read more about common feline health risks in our Health Issues In Sphynx Cats Guide.

2. Bordetella

Bordetella is a respiratory infection that is commonly found in environments with multiple cats, such as catteries or shelters. While not every cat will need this vaccine, it’s recommended for those that are frequently around other cats or travel.

When to Administer:

• First dose: At 8 weeks of age
• Booster: Annually if your cat is at risk

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Vaccination Schedule for Sphynx Kittens

Here is a recommended vaccination schedule for Sphynx kittens:

Age	Vaccine	Booster
9 weeks	FVRCP (first dose)	At 12 weeks
12 weeks	FVRCP (second dose), Rabies (first dose)	At 15 weeks (FVRCP)
15 weeks	FVRCP (final dose), FeLV (if applicable)	Annual boosters thereafter
16-20 weeks	Bordetella (if needed)	Annually if at risk

Pro Tip: Make sure to space out the vaccines appropriately, especially for younger kittens. Overloading the immune system with multiple vaccines at once can be overwhelming for their growing bodies.

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Tips for Maintaining Your Sphynx Cat’s Vaccination Schedule

• Schedule Regular Vet Visits: Keep your vet appointments consistent, and follow up with boosters as needed.
• Keep Records: Always maintain up-to-date vaccination records. This can be particularly useful if you travel with your cat or need to board them.
• Discuss with Your Vet: Depending on your cat’s lifestyle, your vet may recommend additional vaccines or a tailored schedule. Always consult your vet if you have concerns or questions.

For more information on what to expect at your vet visits, check out our post on How to Prepare Your Sphynx for Veterinary Care.

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Common Side Effects of Vaccines

Like any medication, vaccines may cause mild side effects. Most are short-lived and mild, but it’s important to know what to look for:

• Mild Fever: Your cat might be a little sluggish for a day or two after receiving a vaccine.
• Swelling or Tenderness at the Injection Site: This is a common reaction and should resolve within a few days.
• Lethargy: Your Sphynx may be a little tired following the shot. Make sure they have a quiet space to rest.

In rare cases, serious side effects may occur. If you notice any of the following, contact your vet immediately:

• Vomiting or diarrhea
• Difficulty breathing
• Severe swelling or hives

Keeping your cat calm and comfortable after vaccinations is important. To learn more about post-vaccination care, see our How to Keep Your Sphynx Cat Comfortable After Shots.

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Conclusion

Vaccinations are a critical part of keeping your Sphynx cat healthy and protected from dangerous diseases. By following the recommended schedule and consulting with your vet, you can ensure your Sphynx has the best possible start in life. From core vaccines like FVRCP and rabies to optional vaccines like FeLV, each plays a role in your cat’s long-term well-being.

For more on caring for your Sphynx cat, be sure to visit our Ultimate Guide for Hairless Cat Owners,, and explore related articles such as Sphynx Cat Health Guide and How to Prevent Common Health Issues in Sphynx Cats.